IONS IONIS PHARMACEUTICALS INC
2026Q1 · CUSIP 462222100 · Sector: Healthcare & Biotech
Cooling · Breadth rolling over
Holders
492
Δ holders QoQ
-2
Breadth percentile
Top 70%
Whale holders
216
Δ whales
-8
Inst. holding value
$12.8B
New positions
72
Closed positions
74
Price momentum (1Q)
-10.9%
Put / Call
13/17
Breadth history (34 quarters)
Past Lit Events & Aftermath 7 lit events
| Period | Percentile | Next-1Q return | Next-2Q return |
|---|---|---|---|
| 2025Q4 | Top 8% | -10.9% | — |
| 2025Q3 | Top 2% | +13.5% | +2.5% |
| 2025Q2 | Top 15% | +64.7% | +89.3% |
| 2023Q4 | Top 9% | -16.0% | +7.2% |
| 2022Q2 | Top 7% | -0.6% | -13.0% |
| 2019Q1 | Top 2% | +2.5% | -14.3% |
| 2018Q3 | Top 20% | +6.8% | +27.6% |
Options Sentiment
Put holders
13
QoQ: -3
Call holders
17
QoQ: -4
See methodology →
Fundamentals
PE (TTM)
—
EPS (TTM)
$-2.07
EPS YoY
—
Revenue (TTM)
$1.1B
Revenue YoY
+47.5%
Net margin
-30.9%
ROE
-66.5%
Debt ratio
85.8%
FCF (TTM)
-$971M
Dividend (TTM)
No dividend
Quarterly Revenue & EPS (4Y)
Quarterly figures; EPS split-adjusted, early quarters hidden when not calibrable
As of 2026-03-31 · SEC filings (XBRL)
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